Chorionic Villus Sampling (CVS): Understanding This Prenatal Test

If your doctor recommends chorionic villus sampling (CVS), you likely have questions about this prenatal test. Used to detect genetic abnormalities early in pregnancy, CVS can provide critical insights—but it’s not without risks. Here’s what you need to know about the procedure, preparation, and what comes next.


Chorionic Villus Sampling

1. What is CVS?
Key Facts:
  • A prenatal test done between 10-13 weeks of pregnancy.
  • Collects a small sample of placental tissue (chorionic villi) to test for genetic conditions like Down syndrome, cystic fibrosis, or chromosomal disorders.
  • Earlier alternative to amniocentesis, which is performed later.
2. Who Should Consider CVS?
Common Reasons:
  • Abnormal NIPT results or first-trimester screening.
  • Family history of genetic disorders.
  • Advanced maternal age (35+).
  • Previous pregnancy with a chromosomal condition.
3. How is CVS Performed?
Two Methods:
  • Transcervical: A thin catheter is inserted through the cervix to collect the sample.
  • Transabdominal: A needle is guided through the abdomen under ultrasound.
During the Procedure:
  • Takes 10-30 minutes; mild cramping or spotting may occur.
  • Ultrasound guides the entire process for safety.
4. Risks & Limitations
Potential Risks:
  • Miscarriage (1% risk, slightly higher than amniocentesis).
  • Infection or heavy bleeding (rare).
  • Does not detect neural tube defects (requires later ultrasound).
5. Preparing for CVS
Steps to Take:
  • Discuss risks/benefits with your OB or genetic counselor.
  • Wear comfortable maternity leggings for easy access during the procedure.
  • Arrange a ride home, though most women resume normal activities immediately.
6. After CVS: Next Steps
Results Timeline:
  • Initial results in 2-3 days; full karyotype in 1-2 weeks.
  • Follow up with prenatal vitamins and regular checkups.
Emotional Support:
  • Connect with pregnancy support groups if results are concerning.
  • Lean on your partner or counselor to process anxiety or grief.
Final Thoughts

CVS offers early answers but requires careful consideration. Whether you’re weighing risks or celebrating clear results, trust your care team’s guidance. And when you’re ready, channel your strength into planning that joyful baby announcement! 💖

Have questions about CVS? Ask below or explore our guide to prenatal testing!

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